Edoardo Sinibaldi
Chief Technician
About
Edoardo Sinibaldi received a BSc/MSc in Aerospace Engineering (with Honors) from the University of Pisa (Italy) in 2002, after an internship period at Rolls-Royce plc (Derby, UK) during which he studied computational geometry methods for air-breathing engines applications. In 2006 he obtained a Ph.D. in Mathematics for Technology and Industry (with Honors) from the Scuola Normale Superiore in Pisa, where he developed numerical methods for computational fluid dynamics, with application to cavitating flows in liquid propellant rocket engines. Then he moved to Scuola Superiore Sant’Anna in Pisa (The BioRobotics Institute), holding a post-doctoral position until October 2009. During the period, he was strongly involved in competitive fundraising and project technical management (national and European projects in the ICT and MNP areas).
He is with the Italian Institute of Technology (IIT) since November 2009, formerly as Senior Post-Doc then Researcher at the IIT Center for Micro-BioRobotics. Since January 2019 he holds a permanent position as Chief Technician. His research activity bridges modeling (at large, and in particular for biomedical applications), model-based design (in particular for flexible tools) and bioinspired soft robotics (at large, and in particular bioinspired actuation).
Edoardo Sinibaldi authored about 50 papers on international journals and 20 papers on international conferences, 1 book and 2 book chapters. He serves as Reviewer for nearly 50 international journals, and as Editorial Board Member (Associate/Academic Editor) for the following international journals: Scientific Reports, PLOS ONE, International Journal of Advanced Robotic Systems, and Journal of Micro-Bio Robotics. Since 2017 Edoardo Sinibaldi also holds two national scientific qualifications as Associate Professor, namely for Bioengineering and Applied Mechanics.
<For a detailed CV, please, send an email to: edoardo.sinibaldi[AT]iit.it. Thanks.>
Selected Publications
<Research publications and communications, as retrieved from the IIT database, are listed below; I beg to also mention the following complementary items:>
Patents
- Marino, D. De Pasquale, E. Sinibaldi and G. Ciofani. “Sistema e metodo di co-coltura cellulare”
Italian application IT102019000018614, filed on October 11, 2019
Subject: 3D cell co-culture method and system, based on magnetoresponsive scaffolds
- D'Abbraccio, L. Massari, C.M. Oddo, E. Palermo, E. Schena, E. Sinibaldi, G. Terruso and M. Zaltieri. “A tactile sensor device”
Italian application IT102019000003657, filed on March 13, 2019
Subject: sensorized artificial skin for prosthetics and collaborative robotics applications
- E. Sinibaldi, Y. Huan, A. Menciassi and B. Mazzolai. “Adaptively morphing surgical grasper”
International application WO2019155316 (PCT/IB2019/050621), filed on January 25, 2019 (extension of the Italian application IT102018000002432, filed on February 6, 2018)
Subject: compliant surgical grasper for effective and safe interaction with tissue
- E. Sinibaldi, B. Kang and R. Kojcev, “A shape-keeping deployable structure including a pair of robotic systems of the continuum type”
US Patent US10675755 granted on June 6, 2020
Japanese Patent JP6667552 granted on March 18, 2020
European Patent EP3288438 granted on February 27, 2019
International application WO2016174596 (PCT/IB2016/052396), filed on April 27, 2016 (extension of the Italian application TO2015A000233, filed on April 27, 2015)
Subject: flexible tool that can be deployed over a chosen trajectory with the whole body, without using auxiliary supports (the first interlaced continuum robot, with intrinsic “follow-the-leader” capability)
- V. Pensabene, E. Sinibaldi, A. Menciassi, P. Dario, C. Quaglia and P. Valdastri, “Capsule for local therapy by means of an endoluminal plaster in the gastrointestinal tract”
International application WO2013027182 (PCT/IB2012/054239), filed on August 22, 2012 (extension of the Italian application FI2011A000185, filed on August 3, 2011)
Subject: robotic capsule for releasing patches in the gastro-intestinal tract
Popular Science Book
- [book (in Italian)] E. Sinibaldi (Ed.), “Il Fibonacci – Breve viaggio fra curiosità matematiche”, Unione Matematica Italiana, 2011, reprint 2019 (ISBN: 978-88-9633-605-2)
Authors: M. Barsanti, R. Dvornicich, M. Forti, T. Franzoni, M. Gobbino, S.Mortola and E. Sinibaldi
Illustrators: V. Mattoli and E. Sinibaldi
Subject: This book presents math gems, puzzles, and problems originally conceived by the Italian mathematician Franco Conti (and colleagues) for the final session of the Italian Mathematical Olympiad. All problems are solved; relevant points are discussed (more details at: http://olimpiadi.dm.unibo.it/eventi/il-fibonacci/)
IIT Publications
- 2021
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DOI
Real-time imaging and tracking of microrobots in tissues using ultrasound phase analysis
Applied Physics Letters, vol. 118, (no. 1) -
DOI
Soft graspers for safe and effective tissue clutching in minimally invasive surgery
IEEE Transactions on Biomedical Engineering, vol. 68, (no. 1), pp. 56-67 - 2020
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DOI
A machine-learning-based approach to solve both contact location and force in soft-material tactile sensors
Soft Robotics, vol. 7, (no. 4), pp. 409-420 -
DOI
A novel microwave tool for robotic liver resection in minimally invasive surgery
Minimally Invasive Therapy and Allied Technologies -
DOI
Enhanced in vitro magnetic cell targeting of doxorubicin-loaded magnetic liposomes for localized cancer therapy
Nanomaterials -
DOI
Haptic intracorporeal palpation using a cable-driven parallel robot: a user study
IEEE Transactions on Biomedical Engineering, vol. 67, (no. 12), pp. 3452-3463 -
DOI
Light‑assisted electrospinning monitoring for soft polymeric nanofibers
Scientific Reports, vol. 10 -
DOI
Plant-Inspired Soft Bistable Structures Based on Hygroscopic Electrospun Nanofibers
Advanced Materials Interfaces, vol. 7, (no. 4) -
DOI
Polydopamine Nanoparticles as an Organic and Biodegradable Multitasking Tool for Neuroprotection and Remote Neuronal Stimulation
ACS Applied Materials and Interfaces, vol. 12, (no. 32), pp. 35782-35798 -
DOI
Positioning and stiffening of an articulated/continuum manipulator for implant delivery in minimally invasive surgery
International Journal of Medical Robotics and Computer Assisted Surgery, vol. 16, (no. 2) - 2019
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DOI
A variable-stiffness tendril-like soft robot based on reversible osmotic actuation
Nature Communications, vol. 10, (no. 1) -
DOI
Cell Membrane-Coated Magnetic Nanocubes with a Homotypic Targeting Ability Increase Intracellular Temperature due to ROS Scavenging and Act as a Versatile Theranostic System for Glioblastoma Multiforme
Advanced healthcare materials, vol. 8, (no. 18) -
DOI
Correction to: On the reproducibility of expert-operated and robotic ultrasound acquisitions (International Journal of Computer Assisted Radiology and Surgery, (2017), 12, 6, (1003-1011), 10.1007/s11548-017-1561-1)
Computer-Assisted Radiology and Surgery, vol. 14, (no. 10) -
DOI
Design and Development of Large-Area FBG-Based Sensing Skin for Collaborative Robotics
2019 IEEE International Workshop on Metrology for Industry 4.0 and IoT, MetroInd 4.0 and IoT 2019 - Proceedings, pp. 410-413 -
DOI
Haptic feedback in the da Vinci Research Kit (dVRK): a user study based on grasping, palpation and incision tasks
International Journal of Medical Robotics and Computer Assisted Surgery, vol. 15, (no. 4) -
DOI
Neuromorphic tactile sensor array based on fiber Bragg gratings to encode object qualities
Proceedings of SPIE - The International Society for Optical Engineering, vol. 11136 -
DOI
Nutlin-loaded magnetic solid lipid nanoparticles for targeted glioblastoma treatment
Nanomedicine, vol. 14, (no. 6), pp. 727-752 -
DOI
Retrieval of magnetic medical microrobots from the bloodstream
Proceedings - IEEE International Conference on Robotics and Automation, vol. 2019-May, pp. 2495-2501 -
DOI
Tactile Sensing and Control of Robotic Manipulator Integrating Fiber Bragg Grating Strain-Sensor
Frontiers in Neurorobotics, vol. 13 - 2018
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DOI
A 3D real-scale, biomimetic and biohybrid model of the blood-brain barrier fabricated through two-photon lithography
Small, vol. 14, (no. 6) -
DOI
An intravascular magnetic catheter enables the retrieval of nanoagents from the bloodstream
Advanced Science, vol. 5 -
Haptics-enabled palpation for intraoperative tumour detection using a cable-driven parallel manipulator
8th Joint Workshop on New Technologies for Computer/Robot Assisted Surgery, pp. 71-72 -
DOI
Investigation of tip extrusion as an additive manufacturing strategy for growing robots
7th International Conference, Living Machines 2018 -
DOI
Shape estimation based on Kalman filtering: towards fully soft proprioception
RoboSoft – The first IEEE-RAS International Conference on Soft Robotics, pp. 541-546 -
Striving to overcome the (blood-brain) barrier: models for intrathecal drug delivery and infusion into brain tissue
ECCM – ECFD 2018 (ECCOMAS 2018): 6th European Conference on Computational Mechanics, and 7th European Conference on Computational Fluid Dynamics -
DOI
Ultrasound-activated piezoelectric P(VDF-TrFE)/boron nitride nanotube composite films promote differentiation of human SaOS-2 osteoblast-like cells
Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 14, (no. 7), pp. 2421-2432 - 2017
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A 3D biomimetic model of the blood-brain-barrier fabricated with a two-photon lithography approach
28th European Conference on Biomaterials, pp. 232 -
DOI
A numerical investigation of intrathecal isobaric drug dispersion within the cervical subarachnoid space
PLoS ONE, vol. 12, (no. 3) -
DOI
Encapsulation of piezoelectric transducers for sensory augmentation and substitution with wearable haptic devices
Micromachines, vol. 8, (no. 9) -
DOI
Numerical study of intrathecal drug delivery to a permeable spinal cord: effect of catheter position and angle
Computer Methods in Biomechanics and Biomedical Engineering, vol. 20, (no. 15), pp. 1599-1608 -
DOI
On the reproducibility of expert-operated and robotic ultrasound acquisitions
Computer-Assisted Radiology and Surgery, vol. 12, (no. 6), pp. 1003-1011 -
DOI
Piezoelectric Effects of Materials on Bio-Interfaces
ACS Applied Materials and Interfaces, vol. 9, (no. 21), pp. 17663-17680 -
SaOS-2 osteoblast-like cells differentiation is enhanced by piezoelectric P(VDF-TrFE)/BNNTs composite films stimulated with ultrasounds
28th European Conference on Biomaterials, pp. 277 - 2016
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DOI
An analytical model for nanoparticles concentration resulting from infusion into poroelastic brain tissue
Mathematical Biosciences, vol. 272, pp. 6-14 -
DOI
Development and preliminary assessment of a robotic platform for neuroendoscopy based on a lightweight robot
International Journal of Medical Robotics and Computer Assisted Surgery, vol. 12, (no. 1), pp. 4-17 -
DOI
Dual-robot ultrasound-guided needle placement: closing the planning-imaging-action loop
Computer-Assisted Radiology and Surgery, vol. 11, (no. 6), pp. 1173-1181 -
DOI
Osmolyte cooperation affects turgor dynamics in plants
Scientific Reports, vol. 6 -
DOI
Sculpting Soft Machines
Soft Robotics, vol. 3, (no. 3), pp. 101-108 -
Tactile sensor array integrating fiber Bragg grating transducers for biomechanical measurement
6th Joint Workshop on New Technologies for Computer/Robot Assisted Surgery -
DOI
The first interlaced continuum robot, devised to intrinsically follow the leader
PLoS ONE, vol. 11, (no. 2) -
DOI
Toward real-time 3D ultrasound registration-based visual servoing for interventional navigation
Proceedings - IEEE International Conference on Robotics and Automation, vol. 2016-June, pp. 945-950 -
DOI
Unveiling the kinematics of the avoidance response in maize (Zen mays) primary roots
Biologia (Poland), vol. 71, (no. 2), pp. 161-168 - 2015
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A multilayer soft artificial skin for embodied tactile feedback
2015 IEEE International Conference on Robotics and Automation -
A novel plant-inspired osmotic actuator for robotics applications
The 2015 IEEE/RSJ International Conference on Intelligent Robots and Systems -
DOI
On the preliminary design of hyperthermia treatments based on infusion and heating of magnetic nanofluids
Mathematical Biosciences, vol. 262, pp. 105-116 -
DOI
Piezoelectric Nanoparticle-Assisted Wireless Neuronal Stimulation
ACS Nano, vol. 9, (no. 7), pp. 7678-7689 -
DOI
Toward a new generation of electrically controllable hygromorphic soft actuators
Advanced Materials, vol. 27, (no. 10), pp. 1668-1675 -
Towards robotic needle steering using ultrasound visual servoing and a lightweight robot
29th International Congress and Exhibition on Computer Assisted Radiology and Surgery, vol. International Journal of Computer Assisted Radiology and Surgery 10 Suppl 1, pp. S122-S123 - 2014
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DOI
Another lesson from plants: The forward osmosis-based actuator
PLoS ONE, vol. 9, (no. 7) -
DOI
Emerging technologies inspired by plants
Bioinspired Approaches for Human-Centric Technologies, pp. 111-132, Publisher: Springer International Publishing -
DOI
Gold nanoshell/polysaccharide nanofilm for controlled laser-assisted tissue thermal ablation
ACS Nano, vol. 8, (no. 6), pp. 5552-5563 -
DOI
Pulsatile viscous flows in elliptical vessels and annuli: Solution to the inverse problem, with application to blood and cerebrospinal fluid flow
SIAM Journal on Applied Mathematics, vol. 74, (no. 1), pp. 40-59 -
DOI
Towards accurate robot-assisted neuroendoscopy using an ergonomic handling interface and a lightweight robot
2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014, pp. 6876-6879 -
DOI
Wireless robotic capsule for releasing bioadhesive patches in the gastrointestinal tract
Journal of Medical Devices, Transactions of the ASME, vol. 8, (no. 1) - 2013
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Accurate control of a lightweight robotic arm, towards surgical robotics applications
27th International Congress and Exhibition on Computer Assisted Radiology and Surgery, vol. International Journal of Computer Assisted Radiology and Surgery 8, (no. Suppl 1), pp. S128-S129 -
DOI
Exact solution to the inverse Womersley problem for pulsatile flows in cylindrical vessels, with application to magnetic particle targeting
Applied Mathematics and Computation, vol. 219, (no. 10), pp. 5717-5729 -
DOI
Force calculation for localized magnetic driven capsule endoscopes
Proceedings - IEEE International Conference on Robotics and Automation, pp. 5354-5359 -
DOI
Liquid single crystal elastomer/conducting polymer bilayer composite actuator: Modelling and experiments
Soft Matter, vol. 9, (no. 47), pp. 11405-11416 -
DOI
On the existence of hylomorphic vortices in the nonlinear Klein-Gordon equation
Dynamics of Partial Differential Equations, vol. 10, (no. 1), pp. 1-24 -
DOI
Osmotic actuation modelling for innovative biorobotic solutions inspired by the plant kingdom
Bioinspiration and Biomimetics, vol. 8, (no. 2) -
Pulsatile flows in circular and elliptical vessels: solution to the inverse problem, with application to blood flow
MPF2013 – Modelling of Physiological Flows, pp. 59-60 -
SINGER: a virtual SImulator for robotic NeurosurGERy
The Hamlyn Symposium on Medical Robotics, pp. 25-26 - 2012
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DOI
A compliant bioinspired swimming robot with neuro-inspired control and autonomous behavior
Proceedings - IEEE International Conference on Robotics and Automation, pp. 5094-5098 -
DOI
An innovative platform for treatment of vascular obstructions: System design and preliminary results
Proceedings of the IEEE RAS and EMBS International Conference on Biomedical Robotics and Biomechatronics, pp. 731-736 -
DOI
A novel autonomous, bioinspired swimming robot developed by neuroscientists and bioengineers
Bioinspiration and Biomimetics, vol. 7, (no. 2) -
DOI
Artificial adhesion mechanisms inspired by octopus suckers
Proceedings - IEEE International Conference on Robotics and Automation, pp. 3846-3851 -
Innovative Robotic Approaches for Minimally Invasive Intervention in the Human Cerebral Ventricular System
The First NEMB Venice Workshop on Cancer Nanotechnology -
DOI
Magnetic dragging of vascular obstructions by means of electrostatic and antibody binding
Proceedings - IEEE International Conference on Robotics and Automation, pp. 2504-2509 -
DOI
Magnetic propulsion and ultrasound tracking of endovascular devices
Journal of Robotic Surgery, vol. 6, (no. 1), pp. 5-12 -
Mathematical Model for the Cerebrospinal Fluid Flow in the CranioVertebral Junction
Applied Partial Differential Equations in Physics, Biology and Social Sciences: Classical and Modern Perspectives -
DOI
Removing vascular obstructions: A challenge, yet an opportunity for interventional microdevices
Biomedical Microdevices, vol. 14, (no. 3), pp. 511-532 - 2011
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DOI
Adhesion mechanisms inspired by octopus suckers
Procedia Computer Science, vol. 7, pp. 192-193 -
Adhesive nanosheet for topic drug release and therapy in the gastrointestinal tract
4th European Conference for Clinical Nanomedicine -
DOI
A miniaturized mechatronic system inspired by plant roots for soil exploration
IEEE/ASME Transactions on Mechatronics, vol. 16, (no. 2), pp. 201-212 -
DOI
A novel magnetic actuation system for miniature swimming robots
IEEE Transactions on Robotics, vol. 27, (no. 4), pp. 769-779 -
Controlled magnetic propulsion of floating polymeric 2D nano-objects
Advanced Robotics, vol. 25, (no. 8), pp. 1029–1047 -
DOI
Controlled magnetic propulsion of floating polymeric two-dimensional nano-objects
Advanced Robotics, vol. 25, (no. 8), pp. 1029-1047 -
Platform for Magnetic Propulsion and Ultrasound Tracking of Endovascular Devices
The Hamlyn Symposium on Medical Robotics 2011, pp. 29-30 -
Study of the morphology of Octopus vulgaris sucker as a model for innovative artificial adhesion mechanisms
Euroceph meeting 2011: Cephalopod Biology Research in the 21st Century - A European Perspective - 2010
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DOI
From miniature to nano robots for diagnostic and therapeutic applications
2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10, pp. 1954-1957 -
DOI
Magnetic nanofilms for biomedical applications
Journal of Nanotechnology in Engineering and Medicine, vol. 1, (no. 2) -
DOI
Magnetic nanosheets manipulation: Modeling, development and validation
Proceedings - IEEE International Conference on Robotics and Automation, pp. 1604-1609 - 2009
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DOI
Bioinspired Jumping Locomotion in Small Robots: Natural Observation, Design, Experiments
Springer Tracts in Advanced Robotics, vol. 54, pp. 329-338 -
DOI
Hylomorphic solitons in the nonlinear Klein-Gordon equation
Dynamics of Partial Differential Equations, vol. 6, (no. 4), pp. 311-334 - 2008
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A preconditioned second-order linearized implicit formulation for barotropic cavitating flows
5th European Congress on Computational Methods in Applied Sciences and Engineering, pp. 2 pages -
DOI
Cavitation simulation by a homogeneous barotropic flow model
Fluid Dynamics of Cavitation and Cavitating Turbo-pumps (CISM Courses and Lectures 496), Publisher: Springer - 2007
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Implicit preconditioned numerical schemes for the simulation of three-dimensional barotropic flows
Implicit preconditioned numerical schemes for the simulation of three-dimensional barotropic flows, Publisher: Edizioni della Normale -
DOI
Towards the simulation of cavitating flows in inducers through a homogeneous barotropic flow model
CISM International Centre for Mechanical Sciences, Courses and Lectures, vol. 496, pp. 317-351 - 2006
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DOI
A numerical method for 3D barotropic flows in turbomachinery
Flow, Turbulence and Combustion, vol. 76, (no. 4), pp. 371-381 - 2005
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DOI
A numerical study of non-cavitating and cavitating liquid flow around a hydrofoil
Mathematical Modelling and Numerical Analysis, vol. 39, (no. 3), pp. 577-590 - 2004
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A preconditioned compressible flow solver for numerical simulation of 3D cavitation phenomena
ECCOMAS 2004 - European Congress on Computational Methods in Applied Sciences and Engineering - 2003
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Numerical experiments with a homogeneous-flow model for thermal cavitation
Fifth International Symposium on Cavitation, pp. 1-12 (12 pages)
Awards
- [2019/03] Highlight in the 2019 European Research Council (ERC) Annual Report (‘Annual Report on the ERC activities and achievements in 2018’) for the achievements reported in the following research paper:
A. Marino*, O. Tricinci*, M. Battaglini, C. Filippeschi, V. Mattoli, E. Sinibaldi* and G. Ciofani*, “A 3D real-scale, biomimetic and biohybrid model of the blood-brain barrier fabricated through two-photon lithography”. Small, 14(6), 1870024 (1 page), 2018 (* corresponding) [DOI: 10.1002/smll.201702959]
- [2019/01] Research Highlight in Nature: “A robotic vine that can coil itself around the real thing” (https://www.nature.com/articles/d41586-019-00308-5) for the achievements reported in the following research paper:
I. Must, E. Sinibaldi* and B. Mazzolai*, “A variable-stiffness tendril-like soft robot based on reversible osmotic actuation”. Nature Communications 10(1), 344 (8 pages), 2019 (* corresponding) [DOI: 10.1038/s41467-018-08173-y]
- [2018/09] Frontispiece of Advanced Science for the following research paper:
V. Iacovacci*, L. Ricotti, E. Sinibaldi*, G. Signore, F. Vistoli and A. Menciassi, “An intravascular magnetic catheter enables the retrieval of nanoagents from the bloodstream”. Advanced Science, 5, 1800807 (8 pages), 2018 (* corresponding) [DOI: 10.1002/advs.201800807]
- [2018/02] Inside Front Cover of Small 6/2018 for the following research paper:
A. Marino*, O. Tricinci*, M. Battaglini, C. Filippeschi, V. Mattoli, E. Sinibaldi* and G. Ciofani*, “A 3D real-scale, biomimetic and biohybrid model of the blood-brain barrier fabricated through two-photon lithography”. Small, 14(6), 1870024 (1 page), 2018 (* corresponding) [DOI: 10.1002/smll.201702959] [DOI: 10.1002/smll.201870024]
- [2015/03] Front Cover of Advanced Materials 10/2015 for the following research paper:
S. Taccola, F. Greco, E. Sinibaldi, A. Mondini, B. Mazzolai and V. Mattoli, “Soft Actuators: Toward a New Generation of Electrically Controllable Hygromorphic Soft Actuators (Adv. Mater. 10/2015)” Advanced Materials, 27(10), pp. 1637-1637, 2015 [DOI: 10.1002/adma.201404772] [DOI: 10.1002/adma.201570065]
- [2012/05] Finalist (top 5) for the “Best Medical Robotics Paper Award” (hundreds of submissions) at the 2012 IEEE International Conference on Robotics and Automation (ICRA2012, St. Paul, Mn, USA, 14-18 May 2012) for the following research paper:
M. Khorami Llewellyn, P. Dario, A. Menciassi and E. Sinibaldi, “Magnetic Dragging of Vascular Obstructions by Means of Electrostatic and Antibody Binding”, Proceedings of ICRA2012, pp. 2504-2509, 2012 [DOI: 10.1109/ICRA.2012.6224905]
- [2012/07] “2012 TMECH Best Paper Award” (best paper published during 2011 on the IEEE/ASME Transactions on Mechatronics journal) for the following research paper:
B. Mazzolai, A. Mondini, P. Corradi, C. Laschi, V. Mattoli, E. Sinibaldi and P. Dario, “A Miniaturized Mechatronic System Inspired by Plant Roots”, IEEE Transaction on Mechatronics 16(2), pp. 201-212, 2011 [DOI: 10.1109/TMECH.2009.2038997]
- [2002/11] Winner (ranked first) of a PhD position in Mathematics for Technology and Industry at Scuola Normale Superiore, Pisa, Italy
- [2002/11] Winner (ranked first) of a PhD position in Aerospace Engineering at University of Pisa, Italy. I renounced the position in favor of another PhD position simultaneously won at Scuola Normale Superiore (see point above)
- [2001] Winner of a “Socrates” scholarship (granted by European Community; engineering sector) for carrying out my final-year project at University of Toulouse, France. I renounced the position in favor of a research fellowship (internship) simultaneously obtained at Rolls-Royce plc, Derby, UK